by Samuel White | 2nd November 2022
Pathway Journey During my MRes, my first rotation was in Dr Dave Moyes’s group within the Centre for Host-Microbiome (CHMI) interactions. I examined the genetic determinants of antimicrobial resistance in the gut microbiome by screening bacteria and fungi for...
by Samuel White | 2nd November 2022
Pathway Journey 1. The role of Collectin-11 and the Lectin Complement Pathway in COVID-19 infection 2. SNALP-mediated delivery of the cell-cycle inhibitory molecule miR-199a-3p for stimulation of cardiomyocyte proliferation 3. Establishing a pipeline for the...
by Samuel White | 2nd November 2022
Pathway Journey Rotation projects: Investigating viral entry and potential drug candidates for SARS-COV2, Professor Stuart Neil & Dr. Rui Galao Predicting the molecular basis of cancer resistance to radiotherapy, Professor Mahvash Tavassoli & Dr. Shahram...
by Samuel White | 2nd November 2022
Biography My PhD research is focused on the neural representation of trauma memory recall in people who are dual-diagnosed with PTSD and psychosis. Using fMRI and Experience Sampling Method, the aim is to provide a mechanistic understanding of trauma memory recall and...
by Samuel White | 2nd November 2022
Pathway Journey Rotation projects: CRISPR-mediated tagging of LEM2, MAN1 and BAF for investigation of the role of ESCRT-III/VPS4 in peripheral chromatin organisation; Neutralising antibody responses to SARS-CoV- 2 elicited by the ChAdOx1 nCoV-19 vaccine; Function of...
by Samuel White | 2nd November 2022
Pathway Journey Thesis title: Evaluating the long-term effectiveness of a school-based intervention for anxiety and depression in older adolescents (long-term follow-up of the BESST Trial) This study aims to determine whether DISCOVER, a school-based stress workshop...
by Samuel White | 2nd November 2022
Pathway Journey MRes Rotations: 1. The histone lysine demethylase KDM5B regulates gene expression during hippocampus dependent learning 2. Development of a traceable in vitro model of adipogenesis to assess the m6A-methylome during differentiation 3. Deciphering the...
by Samuel White | 2nd November 2022
Pathway Journey My PhD aims to characterise early neuroimaging markers associated with psychiatric disorders in neonates. More specifically, I apply statistical models to identify association between imaging and genetic data in the developing Human Connectome Project....
by Samuel White | 2nd November 2022
Pathway Journey My PhD project focusses on using a newly characterised model of diabetes, the KINGS mouse, to investigate sex differences underlying pancreatic islet biology and its dysfunction in the Diabetes Research group under Dr Aileen King. Biography I graduated...
by Samuel White | 2nd November 2022
Pathway Journey PhD Project: Molecular crosstalk between PLC?1 and STAT3 in Cutaneous T Cell Lymphoma (CTCL) Other MRes rotations: – The role of the gut microbiome on the cardioprotective effect of polyphenol-rich diets – Biophysical regulation of EGFR...
by Samuel White | 2nd November 2022
Pathway Journey Rotations: 1. Stratification of people at risk of psychosis via frequent online assessments of decision-making 2. The effects of stressful life events on the brain in individuals at clinical high risk for psychosis 3. Predicting depression severity...
by Samuel White | 2nd November 2022
Pathway Journey Rotation 1: Understanding interactions between antipsychotic drugs and glucose at the blood-brain barrier: focus on the GLUT1 transporter Rotation 2: Investigating neuronal migration disorders using iPSC and human tissue models Rotation 3: The role of...
