Projects
Our DTP issues a new call for projects prior to interviews taking place. All Core MRC DTP projects are available as 1+3 (MRes + PhD) or as a 4-year PhD. The final decision on which pathway is taken will be made in consultation with candidates who are offered a studentship.
You may contact project supervisors for further information on possible project opportunities. This does not commit a candidate to these laboratories.
2026 Entry – Core Project Catalogue
All Core MRC DTP projects are available as 1+3 (MRes + PhD) or as a 4-year PhD. You may contact project supervisors for further information about project opportunities. This does not commit a candidate to these laboratories.
Measurement of CAR T-cells In Vivo Dynamics with New immunoPET Tracers
BE-MI
BE-MI2026_01
Development of nanoneedles to deliver siRNA therapeutics in glaucoma surgery
BE-MI
BE-MI2026_02
Decoding the Heart–Brain Connection through Advanced Imaging, Machine Learning and Genetic Modelling to Tackle Dementia and Cardiovascular Disease
BE-MI
BE-MI2026_03
Photoacoustic imaging for guiding minimally-invasive sperm retrieval
BE-MI
BE-MI2026_04
Developing Personalisation Strategies for Digital Twin Cardiac Models using Bespoke Clinical Data to Enhance Pre-Procedural Ablation Planning
BE-MI
BE-MI2026_05
Multimodal AI-based Multi-Toxicity Predictive Models in Head and Neck Cancer Patients Treated with Radiotherapy
BE-MI
BE-MI2026_06
Employing Single Molecule Localisation Microscopy (SMLM) to understand HIV-1 innate immunity
BE-MI
BE-MI2026_07
AI tools for linking imaging, epilepsy and neurodevelopment in Tuberous Sclerosis Complex
BE-MI
BE-MI2026_08
Predictive Modelling of Thrombus Formation Using Physics-Informed Neural Networks
BE-MI
BE-MI2026_09
Developing computational methods to improve pregnancy outcomes using wearables
BE-MI
BE-MI2026_10
Real-time intraoperative polarimetric imaging to detect nerves during brain tumour surgery
BE-MI
BE-MI2026_11
Automated radiological assessment for fetal brain MRI
BE-MI
BE-MI2026_12
Advanced diffusion MRI to investigate the connectivity of the developing brain at ultra-high field
BE-MI
BE-MI2026_14
Precision brain circuit targeting via holographic transcranial ultrasound stimulation
BE-MI
BE-MI2026_15
2026 Project: Machine learning based reconstruction to enable ultrafast 3D cardiac MRI exams
BE-MI
BE-MI2026_16
High-field NMR and MRI of 23Na and 2H for metabolic imaging in cancer
BE-MI
BE-MI2026_17
In silico engineering of degradable conjugated polymers for biomedical imaging and photodynamic therapy
BE-MI
BE-MI2026_18
Understanding microstructure of the developing brain using Quantitative Ultrahigh Field Magnetic Resonance Imaging
BE-MI
BE-MI2026_19
Molecular imaging signatures of fibrosis to detect heart failure and response to treatment
BE-MI
BE-MI2026_20
PRECISE-CVD: A precision medicine platform for CVD risk assessment
BE-MI
BE-MI2026_21
How does cardiac 3D morphology age?
BE-MI
BE-MI2026_23
Mesoscale Diffusion MRI Using Ultra-High Performance Gradient Systems: Development and Application in Neurological and Psychiatric Disorders.
BE-MI
BE-MI2026_24
Correlative Imaging of Metabolic Dysregulation in Breast Cancer
BE-MI
BE-MI2026_25
Development of a Novel Microfluidics-Based Fluorescence Lifetime Imaging Flow Cytometer for Live Cell Sorting
BE-MI
BE-MI2026_26
2026 Entry – iCASE Project Catalogue
All iCASE projects are available as a straight 4 year PhD. You may contact project supervisors for further information about project opportunities. This does not commit a candidate to these laboratories.
Deciphering CNS targets for novel CNS-acting therapies in migraine
NS-MH
iCASE2026_01_NS-MH
Deciphering the breast cancer ecosystem
CM-HD
iCASE2026_02_CM-HD
Understanding immunosuppressive stroma-immune networks in lymphoma-burdened lymph nodes to optimise immunotherapy
CM-HD
iCASE2026_03_CM-HD
Design and development of new orally active iron preparation for the treatment of a range of anaemias
CM-HD
iCASE2026_04_CM-HD
Multiomics for precision medicine in chronic pain
CM-HD
iCASE2026_05_CM-HD
NEXT-GENERATION TESTING FOR NEXT-GENERATION THERAPIES: In Vitro Tools for Inhaled Biopharmaceuticals
CM-HD
iCASE2026_06_CM-HD
Targeting ALDH1A1 for the identification and treatment of therapy-resistant cancers
BE-MI
iCASE2026_07_BE-MI
Enhancing antibody-drug conjugate efficacy in solid tumours via modulating macrophage function
CM-HD
iCASE2026_08_CM-HD
Full-length and bispecific monoclonal antibodies to stimulate immune effector cells for the treatment of melanoma
CM-HD
iCASE2026_09_CM-HD
Previous Core Project Catalogue
The projects listed below are for reference only for the 2025 Cohort of MRC DTP MRes 1+3 Students. These projects are NOT availiable for 2026 entry.
Imaging microbial infections with novel gallium-68 labelled aptamers
BE-MI
BE-MI2025_01
2025 Project: Novel theranostics for the imaging and treatment of therapy-resistant breast cancer
BE-MI
BE-MI2025_02
Development of cost-effective, reusable intraventricular brain tumour models (CRIB): Enhancing neurosurgical training through advanced simulation.
BE-MI
BE-MI2025_03
Previous iCASE Project Catalogue
The projects listed below are for reference only. These projects are NOT availiable for 2026 entry.
Do retinoid receptor modulators hold the key to protect and regenerate neurons damaged in Parkinson’s disease and spinal cord injury?
NS-MH
iCASE2025_01_NS-MH
Discovering Epigenetic Signatures of Early Cognitive Decline and Dementia
NS-MH
iCASE2025_02_NS-MH
Elucidating the DNA damage response to radioactive Auger electron emitters for successful anti-cancer combination therapies
BE-MI
iCASE2025_03_BE-MI