Adam Jones

Pathway 0+4

Cohort 2017

0+4 Student

I graduated from KCL with a BSc in Anatomy, Developmental and Human Biology, during which I was also awarded two summer studentships: at KCL in the Randell Division, working on cloning and purification of deletion mutants of proteins; and at UCL in the Laboratory for Molecular and Cell Biology, investigating how ubiquitination influences the endocytic pathways of chemokine receptors. My dissertation project investigated the development and progression of Osteoarthritis.

Following my BSc, I decided to stay with KCL for my MRes in Medical Imaging Sciences, completing a group based multidisciplinary project on Iron-labelling of macrophages for in vivo tracking by MRI. My dissertation project was in mitochondrial biology, investigating new targets for neuroprotection after oxygen-glucose-deprivation.

After my MRes, I worked as a research assistant, at UCL’s Institute of Child Health, gaining further experience in processing biopsies for a clinical trial for muscular dystrophy.

For my PhD, I rejoined the lab I worked in during my MRes project. My PhD is investigating mitochondrial Dysfunction and the evolution of brain damage after neonatal hypoxic-ischaemic insult.

Publications:

Thornton C, Jones A, Nair S, Aabdien A, Mallard C, Hagberg H. Mitochondrial dynamics, mitophagy and biogenesis in neonatal hypoxic-ischaemic brain injury. FEBS Lett. 2017.