Neuroimmune mechanisms of inflammatory bowel syndrome (IBS)

Fibromyalgia is an incurable condition characterized by chronic widespread pain, fatigue, and emotional distress. Despite that >2% (mostly women) of the population live with fibromyalgia, there are no effective therapies. The mechanisms responsible remained unknown...

Epigenetic and circuit abnormalities in neurodevelopmental disorders

Mutations in epigenetic regulators have emerged as a significant risk factor for a diverse group of neurodevelopmental disorders, with most characterised by autism and intellectual disability. We have generated mouse models with mutations in these high risk genes that...