Understanding nuclear growth and remodelling

The nucleus is a key eukaryotic organelle that must grow and restructure in each cell cycle. Tight control of nuclear shape and size is essential for proper cell function, and aberrant regulation of interphase nuclear morphology has been implicated in aging and...

Understanding lymph node determinants of therapy response

The lymphatic network and lymph nodes act as sentinels of the immune system. Lymphatic vessels continually deliver tissue-derived signals for lymph node constituents to assess and initiate an immune response when needed. This system, however may be hijacked by tumours...