by admin | 28th September 2022
Traditionally, a cell’s nucleus has been regarded as a passive organelle that stores and protects the genome, facilitating transcription and replication. However, breakthrough studies have revealed it is a dynamic structure and mechanical sensor for physical cues...
by admin | 7th September 2022
Approximately 25,000 patients are diagnosed with a brain tumour every year in the UK. Meningiomas and pituitary adenomas are the first and third most common primary tumour, accounting for over 50% of all primary brain tumours. Brain metastases affect up to 40% of...
by admin | 7th September 2022
Background: Coronary microvascular disease (cMVD) is a syndrome characterised by anginal chest pain, fatigue, and shortness of breath. More prevalent in women, it is caused by dysfunction of the smallest vessels in the heart, causing transient diffuse patchy...
by admin | 7th September 2022
It has been estimated that more than 10 million deaths per year will occur by 2050 due to antimicrobial resistance (AMR). Therefore, there is an urgent need to develop novel infection-specific imaging techniques that can be translated into the clinical practice as...
by admin | 7th September 2022
Lung cancer is the leading cause of cancer related death worldwide. The presence of malignant mediastinal lymph nodes (MLNs) is important in determining disease stage and appropriate treatment. Non-invasive screening methods using CT and/or PET have low sensitivity...
by admin | 7th September 2022
Background: Cardiovascular diseases (CVD) are a leading cause of morbidity and mortality. Disruptions of electrophysiological mechanisms in the heart lead to cardiac arrhythmias that affectblood supply to the vital organs, and also greatly increase risks of thrombus...
by admin | 7th September 2022
The primary treatment for breast cancer is surgery, which sometimes does not achieve complete removal of all the tumour and therefore requires a further operation. This is then often followed by chemotherapy, radiotherapy and endocrine treatment. The aim of this...
by admin | 7th September 2022
Background & Motivation: Arrhythmogenic Cardiomyopathy (AC) is a prevalent form of structural heart disease which carries with a high risk of sudden cardiac death due to ventricular arrhythmias. Accurately identifying at risk patients for life-saving implanted...
by admin | 7th September 2022
Neuroendocrine tumours (NETs) are rare but poor response to chemotherapies results in a
by admin | 7th September 2022
Aim: To develop a tool that identifies critical abnormalities on MRIbrain scans using deep learning. A clinically validated tool that identifies brain tumours during brain CT or MRI scans does not exist. Immediate identification of a brain tumour potentially allows...
by admin | 7th September 2022
Mapping the structural connectivity of the human brain is one of the main goals of modern neuroscience. Diffusion MRI tractography is the only method that allows researchers probing white matter connections in-vivo, making it a unique tool for research and clinical...
by admin | 7th September 2022
Gestational hypertensive disorders, with preeclampsia (PE, incidence 4-7%) at their extreme end, are a leading cause of maternal death and a major cause of perinatal mortality and morbidity. They also come with a lifelong increased risk for cardiovascular disease. The...