by admin | 7th September 2022
To mitigate the ill consequences of psychosis on people’s life, the NHS and the economy, clinicians increasingly focus on early intervention. Here, the aim is to prevent psychosis from occurring in people at risk of the condition. One way to improve our ability to...
by admin | 7th September 2022
Background: Acknowledging sleep health as a key marker of overall health and the adoption of a systems approach to its study, promotion, and amelioration led to major developments in sleep research. Sleep is recognised as a proxy of health rather than the mere...
by admin | 7th September 2022
Introduction: There is a potential link between neurodegenerative diseases and disordered proteins forming amyloids, which subsequently trigger calcification of brain tissues. In our research laboratories, we have discovered indicative calcification patterns occurring...
by admin | 7th September 2022
Mutations in EPG5 cause Vici Syndrome, a neurodevelopmental disease associated with subsequent neurodegeneration. EPG5 encodes for a protein that regulates autophagy, by controlling the fusion between autophagosomes and lysosomes. Autophagy is an essential...
by admin | 7th September 2022
Characterizing brain development is a fundamental task in neuroscience. Yet, most developmental neuroimaging studies to-date have relied on cross-sectional data, which precludes investigation of developmental changes and has hampered progress in understanding the...
by admin | 7th September 2022
The adult mammalian brain is generally terrible at repairing itself, but some specialised regions can do it naturally. This project will leverage the unique regenerative ability of the olfactory system to ask how neuronal plasticity can influence functional recovery...
by admin | 7th September 2022
Alcohol Use Disorder (AUD) is a highly prevalent disorder. The World Health Organisation has estimated that approximately 3 million people die each year from the harmful use of alcohol. Psychological interventions and pharmacological treatments are widely available,...
by admin | 7th September 2022
The generation of skilled upper limb movements relies on a complex neuronal network including several cerebral cortical and sub-cortical areas. The processing of multi-modal sensory information and its efficient transfer across this network are critical to produce...
by admin | 7th September 2022
Anorexia nervosa (AN) is a disabling disorder typically beginning in adolescence. ~30% of patients respond poorly to psychotherapies, resulting in enduring illness, and the potential to impair development. We have pioneered non-invasive brain stimulation treatments in...
by admin | 7th September 2022
The amygdala, a key limbic brain structure commonly known for its role in higher-order emotional processing, is implicated in stress-induced suppression of gonadotrophin-releasing hormone (GnRH) pulse generator frequency, to cause infertility. Our pioneering discovery...
by admin | 7th September 2022
Adolescents are thought to be more vulnerable to the harmful effects of cannabis than adults. Adolescents are reliably at a greater risk of developing cannabis use disorder (CUD) than adults. Cannabis addiction is the leading cause of <18-year-olds seeking drug...
by admin | 7th September 2022
At present, there are no medications for treatment of Autism core or co-occurring symptoms. There is evidence that the neurobiological underpinnings of ASD include aberrations in brain growth, neuronal patterning, cortical connectivity and altered molecular pathways...
