I am a PhD student in the Srivastava Lab at the Department of Basic and Clinical Neuroscience. In my work, I investigate the biological and molecular underpinnings of psychosis. More specifically, I use human induced pluripotent stem cell-derived forebrain neurons as a model system and a CRISPR/Cas9 approach to investigate the role of a very robust genetic risk factor for psychosis in synaptic formation, maintenance and plasticity.
Before starting my doctoral degree, I was a master’s student on the MSc Neuroscience at King’s College London, where I specialised in Neural Stem Cells and Nervous System Repair Research and did a research placement at Northwestern University. For my final thesis, I investigated synaptic dysfunction in schizophrenia. Prior to that, I graduated from the University of Munich with a bachelor’s in Speech Sciences, where I worked on auditory feedback control in health and disease.
Being part of the MRC DTP was attractive to me because of the diverse and extensive network it provides. It is really great to be in contact with and learn from people who are experts in the many different aspects of neuro- and biomedical sciences. Another advantage of the DTP has been the wide range of courses that are offered.
Apart from my work as a young researcher, I take great pride in being an advocate for womxn and minorities in STEM. At the moment, I am the treasurer for Women of the Wohl, a student-led group that advocates for equality and well-being at our department. You can find out more about us on our website: https://womenofthewohl.com or on Twitter @womenofthewohl.
Sichlinger, L., Cibelli, E., Goldrick, M., & Mittal, V. A. (2019). Clinical correlates of aberrant conversational turn-taking in youth at clinical high-risk for psychosis. Schizophrenia Research, 204, 419-420. https://doi.org/10.1016/j.schres.2018.08.009
Sichlinger, L., Aabdien, A., Raval, P., Tanangonan, L., Srivastava, D. P. Psychosis risk candidate ZNF804A interacts with NT5C2 near synapses and regulates protein translation in cortical neurons. Presented at: 12 FENS Forum of Neuroscience. 11-15 July 2020.