Tek Hong Chung

1+3 Student

In my PhD project, I am investigating how long noncoding RNAs can maintain pluripotency and influence neuronal differentiation through their interaction with RNA binding proteins. Understanding the mechanisms will be important for the identification of therapeutic targets in neurodevelopmental and neurodegenerative disorders. 

I graduated from King’s College London with an MSci in Molecular Genetics. Before joining the MRC DTP, I have worked on various research projects, including the investigation of intrinsic cues in axon guidance during Drosophila ventral nerve cord development, mechanisms of epigenetic regulation of RNA polyadenylation and splicing.  

Returning to King’s and joining the MRC DTP has been a fantastic learning experience. There are many well organised workshops that provide excellent multi-disciplinary trainings in research techniques. The DTP also has a great catalogue of potential projects. The rotations have allowed me to explore my interests and to make an informed choice of my PhD project, knowing that I will enjoy working with my supervisors and colleagues, and that I will have the support I need in my PhD.  

Rotations 

  • Role of long noncoding RNAs in neural differentiation 
  • Molecular dissection of epigenetic signals controlling muscle stem cell behaviour during regeneration 
  • Investigating developmental and epigenetic mechanisms of adipose tissue homeostasis