by Samuel White | 11th September 2023
Neuroendocrine tumours (NETs) are rare but poor response to chemotherapies results in a
by Samuel White | 11th September 2023
Lung cancer is the leading cause of cancer related death worldwide. The presence of malignant mediastinal lymph nodes (MLNs) is important in determining disease stage and appropriate treatment. Non-invasive screening methods using CT and/or PET have low sensitivity...
by Samuel White | 11th September 2023
Background: Coronary microvascular disease (cMVD) is a syndrome characterised by anginal chest pain, fatigue, and shortness of breath. More prevalent in women, it is caused by dysfunction of the smallest vessels in the heart, causing transient diffuse patchy...
by Samuel White | 11th September 2023
Background: Cardiac magnetic resonance imaging (CMR) is widely regarded as the gold-standard imaging modality for evaluating cardiac structure, function, and viability. However, a significant rate of non-diagnostic scans (up to 25-50%) is observed in patients with...
by Samuel White | 11th September 2023
Hypertrophic cardiomyopathy (HCM) is a poorly understood, heritable cardiac disease affecting > 1 in 500 persons. HCM is characterised by progressive enlargement of the primary pumping chamber of the heart, the left ventricle, wherein the heart muscle is abnormally...
by Samuel White | 11th September 2023
Scientific basis: Multi-drug resistant bacterial pathogens are frequent causes of hospital acquired infections which are often difficult to diagnose and treat. Pathogenic bacteria produce and small molecules with high iron affinity (Kaff >1025) known as...
by Samuel White | 11th September 2023
Background: The brain is inherently an electrically conductive organ, but standard imaging modalities are not well equipped to measure its electrical properties (EPs). This is particularly relevant for studying neurodevelopment – pre-clinical studies show that...
by Samuel White | 11th September 2023
Scientific basis / background: Stablishing the causes (i.e. aetiology) of cardiovascular conditions such as hypertension is key for their effective and efficient management. We at KCL have generated initial promising evidence that the heart remodels its 3D anatomy in...
by Samuel White | 11th September 2023
The project aims to develop an automated, machine learning (ML) enabled spontaneous venous pulsation (SVP) detection system, first for widely available optical coherence tomography (OCT) fundal videography, and second for videos acquired from hand-held retinal fundus...
by Samuel White | 11th September 2023
Parallel-transmit (pTx) ultra-high field MRI using multiple radiofrequency (RF) transmitters demonstrates impressive advantages for high-resolution anatomic and functional imaging of the human body. By adjusting the RF phases and amplitude of individual transmitters...
by Samuel White | 11th September 2023
Gestational hypertensive disorders, with preeclampsia (PE, incidence 4-7%) at their extreme end, are a leading cause of maternal death and a major cause of perinatal mortality and morbidity. They also come with a lifelong increased risk for cardiovascular disease. The...
by Samuel White | 11th September 2023
Mapping the structural connectivity of the human brain is one of the main goals of modern neuroscience. Diffusion MRI tractography is the only method that allows researchers probing white matter connections in-vivo, making it a unique tool for research and clinical...